Poorly controlled asthma: is it really asthma?

Adult-onset asthma: is it really different?

Asthma that starts in adulthood differs from childhood-onset asthma in that it is often non-atopic, more severe and associated with a faster decline in lung function. Understanding of the underlying mechanism of adult-onset asthma and identification of specific phenotypes may further our understanding of pathophysiology and treatment response, leading to better targeting of both existing and ne...

Severe asthma is really uncommon

We describe the case of a 10-year-old girl with a history of severe persistent asthma and exercise-induced-asthma, controlled using an appropriate treatment with inhaled corticosteroid-long-acting beta-2 adrenergic agonists (ICS+LABA) and leukotriene receptor antagonists. She was healthy until the age of 8 years, when she presented two episodes of radiologically diagnosed pneumonia. After that,...

Asthma is a Serious Danger

  میزان مرگ و میر آسم طی دهه گذشته بطور چشمگیری تغییر کرده است. با مبتلا کردن ۱۵ میلیون آمریکایی میزان مرگ و میر در سال ۱۹۷۸، به رقم ۱۸۷۲ نفر و ۹ سال بعد، به بیش از ۴۰۰۰ نفر رسید. علت چنین افزایش چشمگیری روشن نیست. علل احتمالی عبارتند از کاهش ظرفیت تنفس، استفاده بیش از حد از داروهای استثنائی و استنباط غلط بیماران و نیز مراکز درمانی نسبت به شدت بیماری است. بررسی دقیق، معالجات مناسب و آموزش به ب...

Poorly perceived asthma.

Asthma: where is it going?

Asthma is characterized by reversible airway obstruction, airway hyperresponsiveness, and airway inflammation. Although our understanding of its pathophysiological mechanisms continues to evolve, the relative contributions of airway hyperresponsiveness and inflammation are still debated. The first mechanism identified as important for asthma was bronchial hyperresponsiveness. In a second step, ...